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Escherichia
coli (E. coli) causes about 80% of UTIs in adults. These
bacteria are normally present in the colon and may enter the
urethral opening from the skin around the anus and genitals.
Women may be more susceptible to UTI because their urethral
opening is near the source of bacteria (e.g., anus, vagina) and
their urethra is shorter, providing bacteria easier access to
the bladder. Other bacteria that cause urinary tract infections
include Staphylococcus saprophyticus (5 to 15% of cases),
Chlamydia trachomatis, and Mycoplasma hominis. Men and women
infected with chlamydia trachomatis or mycoplasma hominis can
transmit the bacteria to their partner during sexual
intercourse, causing UTI.
Sexual
intercourse triggers UTI in some women, for unknown reasons.
Women who use a diaphragm develop infections more often, and
condoms with spermicidal foam may cause the growth of E. coli in
the vagina, which may enter the urethra.
Urinary
catheterization (small tube inserted into the bladder through
the urethra to drain urine) can also cause UTI by introducing
bacteria into the urinary tract. The risk for developing a UTI
increases when long-term catheterization is required.
In
infants, bacteria from soiled diapers can enter the urethra and
cause UTI. E. coli may also enter the urethral opening when
young girls do not wipe from front to back after a bowel
movement.
Other
risk factors include the following:
-
Bladder
outlet obstructions (e.g., kidney stones, BPH)
-
Conditions
that cause incomplete bladder emptying (e.g., spinal cord
injury)
-
Congenital
(present at birth) abnormalities of the urinary tract
(e.g., vasicoureteral reflux)
-
Suppressed
immune system
-
Being
uncircumcised
-
Certain
blood types enable bacteria to attach more easily to cells
that line the urinary tract, causing recurrent UTIs.
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